POP

Scientists uncover biological underpinnings of synthetic mesh failures

How much time have you spent thinking about urinary incontinence? Chances are, if you are experiencing it, you’ve spent quite a lot of time considering your treatment options. After menopause, as many as 50% of women may experience urinary incontinence. Many women have turned to mesh implants that are inserted during a simple procedure. These synthetic mesh devices have been used to treat both urinary incontinence and pelvic organ prolapse, often with great results. Unfortunately, the implants were not without side effects. In 2008, the FDA issued a Public Health Notification warning of severe complications from these implantable meshes. Many women experienced “mesh erosion” in which the mesh wore through the vaginal lining, causing significant pain and often necessitating repeat surgeries. Scientists from the University of Pittsburg have now published new data on exactly how the body interacts with these implants.